What exactly do you have in mind? I am not sure if I understand your question? What exactly do you use yourself?
And in the desktop tools you usually have more control over the quality which makes it impossible to compare to each other.
btw I tried guetzli a while ago, it was a joke. Lots of hype, much worse results compared to tinypng for example. And it took minutes to process 2 mpix image on MBP.