Well said.
But: I have been using mu4e + Emacs for email for about two years now. I would seriously recommend anyone who already uses Emacs -- and especially if you use org-mode -- to look into it. Not because you score nerd points for reading & composing email in Emacs (frankly, you look ridiculous) but because it might just hook in perfectly with your workflow. I hardly touch any of the power user features, I do very little customization, and still it is by far the best way for me to manage my email. I also use it side by side with a web client (both Fastmail and Gmail) and switch if I need to.