Wolfram doesn't give even a simple example of how two particle-like structures might repel or attract each other in an isotropic fashion in a network system (or any other system in NKS). That doesn't prove it's impossible, but if it is possible neither Wolfram nor anyone else seems to have any idea how to even get started.
But say you solve that problem too -- there are many more problems after that. How do you encode the other properties of a particle like mass, charge, spin and momentum into this pattern? How can patterns attract and repel each other at long distances like real particles do?
These problems are probably all solvable, but my point to the original poster was that it's harder than it seems at first, and it's not something that's amenable to a simple search of the state space of possible automata.