>>I'm not saying that investigating the $250k is not important; but just not more urgent than the $2k theft.
Absolutely not. Ignore the case when this 250k was your entire life savings (30-40 years of saving remainder of your salary every month and slowly building savings for retirement).
It could be mortgage money which you are about to buy a house with or it could be company money for payroll. Suddenly employees of a small business don't get paid. Those employees of course have to pay mortgage/rent/medical bills and suddenly paycheck they counted on doesn't come. This could affect many people in very negative ways.
I think $250k stolen should definitely get a priority to be investigated by agents over $2k stolen as it is more likely it will mess up lives of many people in a bad way.