Yes, but the counterparty risk - in case of a real crash - is pretty high IMHO.

Anyway, a couple of ways to do so:

You can short BTC using "USDT" on poloniex: https://poloniex.com (USDT is a cryptocurrency theoretically pegged to the USD, but their peg hasn't be very stable lately)

Another way, which could in theory be better (or not) is using options: https://www.deribit.com/

If you can find someone to take the opposite bet sure, why not?