Transhumanism can be viewed as a fusion of what already is given. It is a mere combination of two systems, artificial and natural, that might as well have evolved similar to a symbiontic relationship. Before the actual enchancement, we will have a phase of mingling technology like we do naturally today, extending knowledge beyond our own entity, sharing information and boosting awareness of critcal tasks through the world wide web. Then there will be enchancement. If there is manipulation through it, ethical or not, the world needs to be influenced before we reach critical mass as a species and by our byproducts. Else there won't be no need to ask such questions much longer anyway.