Would definitely be interested in finding more studies on extremely low sodium diets (especially on possible long term side effects), but finding information has been quite difficult.
Would definitely be interested in finding more studies on extremely low sodium diets (especially on possible long term side effects), but finding information has been quite difficult.
That seems like a potentially significant change you're ignoring.
It has been suggested that "leptin resistance is considered a primary risk factor for obesity. It has been hypothesized that dietary cereal grain protein could cause leptin resistance by preventing leptin from binding to its receptor."
"Similar to what is observed in chronic inflammation, chronically elevated leptin levels are associated with obesity, overeating, and inflammation-related diseases, including hypertension, metabolic syndrome, and cardiovascular disease."[2]
1. https://bmcbiochem.biomedcentral.com/articles/10.1186/s12858...
Bread and potatoes have a big impact on blood glucose levels. Actually, potatoes have a glycemic index that's even higher than table sugar.
Diet is such a complex thing that it's really difficult to control for.