It seems to expect more precise queries, while Google is geared toward "close enough" searches. I've found that DDG is often preferable when I have an exact phrase in mind. Google is sometimes too helpful, correcting errors that are not actually errors and failing to take some queries literally enough.
The main issues I have with DDG are that it doesn't seem to prioritize recent results (which can be good, but usually isn't) and it fails at local results, which is basically by design.