Definitely. There is no potential for charter operations for a plane with no toilet. Many companies learned it the hard way trying to operate the Eclipse. With no charter market, plane is dead because there are never enough hobby pilots to buy it to pay back sunk costs. For low-range flights <600 miles where operating without toilet is feasible, helicopter works better.
The way I understand it growing up, if you can fly further than a normal human can wait to go to the restroom, you probably need one on board.