I would love to have the opportunity to explore the concept of hyperlocal. Using the web to help bring local communities closer together. Never really had the opportunity yet.
I myself, work mainly on projects related to museums, culture, green economy... In the projects I accept I try to find a balance between money I can get and how I view it as work for the greater good. A very hard balance and a very subjective one.
Also have some friends that are a lot into open data which is also an interesting area to explore.