Overall, this usually provides a 30%+ increase in revenue over running just AdSense.
I wouldn't say its better, but I think I rake in an average of about $115 a year from running ads on my site. Of course, it all depends on your traffic, and they only payout in $100 increments.
You'll get a bigger cut and have more control.
CJ, LinkShare, Share-a-Sale.
PPC is the easiest way to add monetization to your site and the least lucrative.