What makes you think that modern cars have to be replaced many times more often? It seems like replacement intervals have actually been creeping up.
Most used cars I've looked at in dealerships (as opposed to the Craigslist/Uncle Henry's as-is-where-is private sales) were overwhelmingly former lease vehicles.
It replaced a car that had 190k miles from around 2000. Its worst problems were a bad A/C compressor (replaced at ~100k miles) and a slipping clutch (it was the original clutch). The plugs and wires were replaced once during its service.
Modern cars are amazingly reliable and amazingly safe compared to their predecessors.