I'm just a runner, not a hunter. A couple years ago, I was out on a run when I was quickly set upon by two adolescent German Shepherds. I was on the opposite side of the street, but they left their property (they were out playing fetch with their owner). Before I knew it, they were circling me and then one took a bite of my thigh.
To this day, I'm astonished by how quickly it happened. I'm virtually certain that even if I'd had a weapon, I would not have been able to use it in time.
These dogs were not attacking me either. The bite was playful, from a poorly trained adolescent dog.
I'm pretty sure that even with a gun, I'd be scared of a pack of wolves. A canine can move very quickly and violently.