I totally agree PyCharm's navigation and debugging functionality are fantastic. That said, when I last tried it (about 2-3 years ago), my Python code ran incredibly slow. I have a relatively large but not huge Django based python project (~2M LOC with libraries), but with debugging enabled my Python code practically ground to a halt. It's possible I misconfigured the debugger, and I can't remember how long I spent trying to get it to work, but it was discouraging enough that I dropped it.

My debugging now is just logging.info and some fancier log aggregation tools, but still feels like the early 1990s.