Also troubling about Boston startups is the frequency with which the best get bought by SV companies. Seems to me that this also tends to limit local growth. So not bad at all, but not what might have been either.
I feel like this is one of those SV bubble things, that a place has to have a "scene" in order to have startups (and only SV has a "scene"). There are thousands of successful businesses everywhere, even ones that would be considered "startups". The only difference between SV and any other city is people are willing to throw money at ideas with no chance of ever turning a profit which isn't really a sign of a healthy ecosystem.
I wonder how many people who say "you need to be in Silicon Valley to run a successful startup" use MailChimp (Atlanta) or RunKeeper (Boston), or Venmo or Squarespace (NYC) or Duo Security (Ann Arbor, MI) or Dwolla (Des Moines, Iowa).
Whenever I hear "startup scene", I think of Juicero and wonder if that kind of company could ever actually ship a product if they were based anywhere but Silicon Valley. And I wonder how much that actually says about the "startup scene".
According to WalletHub, SF rates pretty darn far down the list of best places to start a business: https://wallethub.com/edu/best-cities-to-start-a-business/22...
Maybe the number of success stories coming from SF has more to do with the sheer number of businesses that are started there? If 100 businesses are started in SF and only 5 in Tulsa, even if only 10 of the startups survive in SF while all 5 survive in Tulsa, people would still say "SF has twice the number of successful startups" even though 100% succeeded in Tulsa vs just 10% in SF.
I grew up in the Boston area as well, thought I would stay there my whole life, and a lunch conversation with Drew was actually instrumental in changing my mind about moving to Silicon Valley. The reason is precisely that: the Boston business climate is so conservative that you really can't get resources unless you're working on something that has made money for other people. I actually don't think I'd start a company in the Bay Area now if I didn't already live here and have a wife with family here - there's usually a long period of learning your market before you have anything fundable, and it's better to spend that in a region where rent won't cost you a fortune. But the Bay Area remains the best place, bar none, to scale a business, and it's quite likely that if your nascent business has any serious growth potential, it'll be fodder for a Silicon Valley competitor with $100M in funding.
And some off then even work? like Snapchat, Facebook, Twitter, AirBnB, Uber etc.
Looking back to the time they where funded all these ideas look like sure lossers.
The local scene matters. Most importantly, it affects the rate of people starting companies. If there are other startups around you, you can learn from them. You may not think things like accelerators, meetups, and startup-related college talks matter, but that stuff is really key for creating first-time founders.
As far as investors, it matters in angel + seed rounds, but matters far less past that (because you can fly to your investors). But having a way to access those early investors (when founders are still learning how to talk to investors, and trying to raise the money to run a company full-time) is very important.
I think it's probably a lot easier for a second-time founder to start a company outside of a "scene". But even in that case, having a larger talent pool is nice, and the convenience of being closer to investors.
All of the cities you mentioned (besides Des Moines, Iowa) have at least some sort of startup scene that I've heard of. It's a power-law distribution, but for most founders the value of moving from Des Moines to NYC, or from Boston to SV, is pretty compelling.