1) when you make juice, you leave some of the most wholesome parts of the fruit behind. The skin on an apple, the seeds in raspberries and the membranes that hold orange segments together — they are all good for you. That is where most of the fiber, as well as many of the antioxidants, phytonutrients, vitamins and minerals are hiding. Fiber is good for your gut; it fills you up and slows the absorption of the sugars you eat, resulting in smaller spikes in insulin.
2) when you drink your calories instead of eating them, your brain doesn’t get the same “I’m full” signal that it does from solid food, even though you wind up consuming far more calories in the process.
[edit: clarified text is quoted from the article]