Block Me If You Can: A Large-Scale Study of Tracker-Blocking Tools [pdf]
sba-research.org
sba-research.org
True, you can't block trackers on domains that aren't blacklisted, but on the other hand you can block trackers for all devices on the network.
I had Ghostery installed for years (gets one of the highest blocking marks) but I didn't like that it slowed down Chrome, hogged a lot of memory, and has the capability to send traffic back to a company.
The best defense against tracking, in my humble opinion, is compartmentalization. If you're concerned about X and Y being associated through tracking, compartmentalize them. Use multiple personas, each with its own VM(s) and chains of VPNs and Tor. I don't care at all if everything that Mirimir does online is tracked and associated.
But it's very promising.