These types of comments are always hilarious. Really? You think we've topped out on 1bn dollar companies in the year 2017? AI, Self Driving Cars, Improvements to Flying, SPACE!? You honestly think there's nothing left to invest in?
As for the other two categories, only SpaceX is relevant in the spacelaunch world, and I don't think they're going public anytime soon. I don't know of any startups that I would say have a decent chance in commercial aviation.
Of course, there's all sorts of machine learning and related AI-ish things that are potentially useful in the interim.
Fully agree on the other points.