I like how LSD was discovered [0]. It's so potent that it can be absorbed just by skin contact, that's why police must use gloves when seizing it.

Imagine yourself coming home with your bicycle and having a massive (250 ug) LSD trip only having experienced it once, pretty scary and interesting at the same time [1].

[0]: https://en.wikipedia.org/wiki/Albert_Hofmann#Discovery_of_LS...

[1]: http://www.thegooddrugsguide.com/articles/lsd_accident.htm