I thought the best chapter was on Phillip Greenspun of ArsDigita. Phillip was forced out of his own startup by his board and he eventually maneuvered behind the scenes to regain control.

If there's a "Founders At Work 2.0", more stories about failures, mistakes, and how people learned from those failures+mistakes would be super helpful. Most startups aren't an overnight success or a unicorn with "rocketship" style growth. Learning more about the non-sexy, non-linear successes can be just as useful than reading about the unicorns.