Users won't notice when something is perfect. But when anything is misaligned, it sticks out like a sore thumb.
Dont give up, we care about the pixel.
No, it really does not. Users don't care for Drudge Report not being perfect, Craigslist not being perfect, and thousand other huge volume sites.
And besides, Craigslist and Drudge Report don't look nice, but they still look aligned in the places where they're trying.
Nice counter-argument, but I'd still say no. There are still tons of sites that try but are still off, and people don't care at all, they're still huge.
It's all about the service, unless one's is catering to OCD customers.
- Stackoverflow horizontally scrolls at 1024x768. Reaction: Growl at VCs, zoom site to 90%.
- "?" button on Q/A editing toolbar pops down a little explanation bar that is misaligned off-by-one to the right (when site zoom is at 90%). Reaction: fidget in chair and be sad :(
So it is the little things!
PS. I rehashed the 1024x768 thing recently, not much happened. https://meta.stackoverflow.com/questions/344521/request-for-...