Humans evolved as social animals. Everything we've always done has been in groups. When you are growing up, you spend most of your waking time in the company of other people (school). The ones who don't, who are homeschooled alone, turn out "weird". Until the modern advent of telecommunications, working has meant being physically collocated with other people. Spending most of your waking hours alone at home is an unusual thing to do; we're not adapted for it, and it's tough.
100% telecommuting doesn't work for a lot of people, maybe even the majority of people. It definitely doesn't work for me. Coworking spaces are one solution, but I only have a short commute anyway, so I'm just going to go into the real office.