I don't like the idea of these Super National organizations that politically and economically integrate people so tightly.
Really it's more about having our global society so tightly integrated and efficient. It means power (economic and political) goes to a select few people who get better and better at holding on to it.
These crazy large banks that are so freaking tightly integrated are the worse example. A crisis at one bank triggers a global meltdown. We don't want a global meltdown so we bail out the banks, making them bigger and more powerful, exacerbating the problem.
The more tightly controlled everything is makes our system so fragile.
If the UK is more separated economically from Europe, if one or the other has an economic crisis the separation will lead to less drastic economic crisis.