There's really not much noise in that expression, just the "(,,)", so maybe 4 chars that an opcode could save.
As for 3), is that really possible? If you profile most modern frameworks, they're already fast enough that most of the time is spent in rendering, not in javascript DOM manipulation. So even if you cut short your js before 16ms (60fps), you have no idea how long the browser is going to take to render your changes. Plus, the browser will be doing extra work, since it needs to render all the frames in which you've only done part of your updates.