I am more impressed when people ask about overall company direction and current challenges. It demonstrates to me that they're interested in the company as a whole, where it is going, and how they see themselves fitting in and contributing.
Optimizing for originality seems the wrong criteria as an interviewee if you are genuinely trying to feel out the company and what working there might be like.
As an interviewer don't you think it's more telling to see how an interviewer responds to the answers you give? I mean, asking a prepared question is kind of low effort regardless, but using a question to initiate discussion, that shows real engagement.
Dunno. Just thinking out loud here.
The second type of question that I mentioned above is more of the type: "What can I bring to this role and how I can I contribute to this company?"
As an interviewer, if I don't get any of the second type of question it makes me question their passion and ownership a bit.
The best way to make do in this case is to ask questions that will help me gauge if I would be happy here even if I'm working on a CRUD app.
It's the people that make it worthwhile after all :)