Testing would be the easy part, in some cases it would be easier than DOM because you can do image diffs... The harder part is BUILDING IT.
I've gone back on forth on this topic quite a bit. I used to be a strong believer you should virtualize everything. But then you've broken in-browser search, and you find yourself having to write and support even more code. Using canvas? Say goodbye to accessibility. Now, I'm not saying this is the case for your use-case, but I think that in some cases it's worth seriously reconsidering the design and just going with a simple table that leverages built-in browser functionality and traditional pagination. If you have so much data that you struggle to load and display it with JS, it may be a good idea to take a step back and explore alternative strategies for presenting the data to your users. As an extreme example, a 1 million by 1 million table would probably contain too much data for any consumer to really make sense of it. I only say this because I had a couple experiences where having heard that might've helped keep things simpler. I'll still happily reach for react-virtualized when I find a situation that merits its use.
[0] https://bvaughn.github.io/react-virtualized/#/components/Gri...