- We keep track of how domains have been used before (so as to mitigate if not entirely predict that QC). We are trying to encode that expertise in a way that is intuitive and frictionlessly sharable. The more people use it the more helpful it becomes. We help encode biological institutional knowledge.
- We collaborate with DNA synthesizers so that you just do the designing, and we help get you the designed DNA to your bench at a reasonable cost. You get exactly the sequence that you want, not what someone gave your neighboring lab's buddy sometime ago, or what some restriction enzyme/quick-change let you that's probably good enough. We alleviate the pain of cloning.
- We help you build entire sets by dragging and dropping: "I want these three fluorophores upstream, these 4 linkers on these proteins of interest" - Boom! Buy! Done! (in literally as much time). We make efficient high-throughput design.
- It is true, there are many proteins that are note entirely modular. But there are many more than 10 examples of proteins designed exactly that way (see Addgene's database). Biology is hard. We help you prevent failure buy being able to see how other successes have been achieved, prevent stupid mistakes, and get you your material to you as quickly and cheaply as possible. If your design does fail, it has failed faster and with less sunk cost than if you had to do all the construction yourself.
- Finally, because combinatorial design and purchasing is reasonably priced (and you don't have to do the construction work), you can order an entire logical set of proteins to actually figure out which would work and which would not. When I cloned I made some tiny fraction of what I expected to work purely because cloning was so painful - and if that small fraction failed I didn't even bother to figure out why or what would have worked.
I'd appreciate any feedback you might have.