I'm pretty sure the standard definition of primes permits only natural numbers.
EDIT: better yet, the proper formulation with regard to all integers would be "integers having a prime factor p such that |p| < 100"
I think the terminology is a convenience - so many results pertain to 2, 3, 5, ... that it's easier to let "prime numbers" refer to them, rather than to have to qualify everything by saying "positive primes" or taking absolute values.