There's nothing in principle that stops a machine from creating art. Even, better art than any person could do. So once that happens, where are we left?
Meaning isn't something physical in the universe. Meaning is an emotion. It's what you feel when you're working towards something that you believe has some greater importance. With all opportunity to work towards anything taken away, life will become meaningless by definition, unless humans are left with some pseudo-artificial challenges to push against.
Zookeepers put the animals' food inside a metal box with a small hole, so the animals have to do work to get it out. It's good for the animals to have something to work towards, and they're too dumb to realize they're being manipulated. Maybe that's our future. With WoW and Clash of Clans, etc, sometimes it feels like we're already halfway there.