I switched to dvorak awhile ago. I still catch myself having a frisson of pleasure in the act of typing some words; typing feels like an intricate finger tango at times.

The only gripe I still have with it is every single time I type ls -alx

Check out, if you haven't, http://mkweb.bcgsc.ca/carpalx/

http://mkweb.bcgsc.ca/carpalx/?worst_layout is indeed the stuff of nightmares.