I've used Backbone/Marionette, Angular, and React at this point. I think Backbone/Marionette is the best framework so far maybe because it was the first one I did a big project on. Backboe/Marionette has very clear separation of concerns...the only true MVC framework among the 3. React is great for reusable components, but the tooling around it is so backward...I feel like I'm writing a java application and I need to piece things together.

Btw I'm working on a django/react application and I have yet to figure out how to not duplicate the react routes in django. It defeats the purpose of a single page app because I don't want to reload all the same resources because a small piece of the app changes...how do you fix this?