Major Key: Avoid compile steps as long as possible.
No Babel, no Webpack, no browserify, no JSX. You can use React without any of them. You'll get to them when you really need them eventually. Maybe. Only one of the above I use is browserify.
Why?
As a developer, your key job is keeping complexity down. Doesn't matter if everyone else implicitly gets it. If it's complex to you, don't feel forced to use it. If you can get by without it, do so. When you eventually get it, it wouldn't be that much of a struggle.
You'll still need to look up apis, function args and options, but that's just forgetting how to tell the computer what you want. Very different from not understanding why you need each piece or how to put them together.