Yes, Cirru, in 2013, which is only a language front-end that compiles to JavaScript, Clojure, JSON or HTML.

* http://cirru.org * text.cirru.org (temporary solution) * https://news.ycombinator.com/item?id=13773813

I was trying to explore the expressiveness of graphical editing(at first using indentations). And it ends up with a nice tree editor that I can editor as DOM. With DOM, the layout of the code is actually the layout of AST controlling by algorithms that is responsive to screen size and AST structure.