Secure boot has 4 types of keys:
The signature database (db) and forbidden signature database (dbx) contain a whitelist and blacklist respectivly of keys, signatures, and hashes that are trusted to run.
Updates to either of the above lists must be signed by a Key Exchange Key (KEK). Most implementations allow multiple Key Exchanges Keys.
Updates to the list of Key Exchange Keys must be signed by the Platform Key (PK). Most implementations only allow 1 PK, and that PK is Microsoft's.
This means that any binary run on a secure boot machine with Microsoft's PK has a chain of trust rooted at Microsoft.
It may be possible to update the PK before transitioning the system to secure mode; but most consumer devices ship already in secure mode. This is different from simply disabling secure boot, which would still not allow you to update PK (for obvious reasons).
EDIT: It appears that it is called "user mode" and "setup mode" instead of secure mode.
Also it seems that some systems allow you to re-enter setup mode from the "bios" [0].
On an unrelated note, what do we call the firmware provided settings app now that it is no longer part of the BIOS.
[0] https://wiki.gentoo.org/wiki/Sakaki%27s_EFI_Install_Guide/Co...