https://developer.mozilla.org/en-US/Add-ons/WebExtensions/AP...
With this pref enabled, advertiser X will serve you different cookies on site A and B. They won't be able to track your browsing history from site to site. However, this breaks a lot of sites that depend on third-party services for login authentication or comment systems.
Here is the Firefox bug where you can report broken sites:
Essentially building a new container per origin.
privacy.firstparty.isolate
If a FF PM is reading this: being able to register a domain for a container type would be a killer feature.