If I ever get up the nerve to give it a real try, I will certainly test the slack's patience for stupid questions :)
The .NET reference is useful if you are reading through code and maybe to modify it slightly, but I find it (and class hierarchy style docs in general) to be close to useless if you are writing new code and new to the library. Using a new library in Python (especially one that's heavily object oriented), I often find it easier to learn from tests instead of the docs. Reference docs are often inaccurate or too verbose or show no sense of importance or are just poorly written. Tests are straight to the point, include examples, and tend to focus on the most important parts of the library.
The MSDN docs have quite a bit of "How do I..." content, but unfortunately F# is seemingly always blank as an example.
Combine this with a huge proportion of commonly used third party libraries being .NET rather than F# libraries, and so much of the .NET infrastructure you need to use being C# focused, and as a newcomer you are paralyzed.
If F# is serious about building a community of more than just C# converts, they need to recognize that the convenience of .NET for people who already know it carries a commensurate tax for everyone who doesn't. It's harder for me to learn .NET as an F# user than a C# user. It's harder for me to learn to use NuGet as an F# user than a C# user. It's harder for me to learn to use Visual Studio as an IDE with F# than C#. In everyone of these scenarios, you're running up hill because examples and documentation and interfaces are all for the majority, which you won't be.