• you've probably entirely emptied out everything in your intestines+colon by then;
• you've possibly starved your intestinal microbiome enough that it's stopped excreting any metabolic byproducts;
• you've probably starved any bacteria hanging out in your mouth/sinuses/tonsils/adenoids, and so breathing + drinking water + saliva has finally had a chance to actually get rid of those;
• any of the inflammatory compounds that get into your bloodstream from your food, have been removed, so your total tissue inflammation is lower than it ever is otherwise (like being on corticosteroids, sort of);
• since your liver/kidneys aren't dealing with a constant stream of input, they can 1. clean themselves for a change, and 2. clean "lower-priority" stuff out of your blood;
• and once they've done that, now they can just shut down and stop spending energy or consuming metabolites.
Presuming you're also drinking a normal amount of water,
• your blood pH and O2 sat. are likely maintained much more closely than they are when you eat food, which allows your organs and your immune system to function slightly more optimally.