https://en.wikipedia.org/wiki/Insulin> promoting the absorption of, especially, glucose from the blood into fat, liver and skeletal muscle cells
> in the tissues that can carry out these reactions, glycogen and fat synthesis from glucose are stimulated
> The breakdown of triglycerides by adipose tissue into free fatty acids and glycerol is also inhibited
> Increased lipid synthesis – insulin forces fat cells to take in blood glucose, which is converted into triglycerides (aka fat)
> Increased esterification of fatty acids – forces adipose tissue to make neutral fats (i.e., triglycerides) from fatty acids
> Decreased lipolysis – forces reduction in conversion of fat cell lipid stores into blood fatty acids and glycerol
Kcals in kcals out fails practically every overweight person over 30 I know. But they won't hear about biochemistry. Poor folks aren't even eating that much, but what they do eat sufficiently inhibits liberation of the many-months-worths of energy stores they carry around all day. Don't envy them, full of energy yet out of energy!