There is real work to migrate you application to use Cloud Spanner. Your schemas and queries will work with some tweaking but we don't have ORM support at beta.
We are going to produce some additional collateral on migrating from popular RDBMS, but the Quizlet post is the best reference right now for migrating from MySQL.
https://quizlet.com/blog/quizlet-cloud-spanner
We have released client libraries for Java, Go, Node and Python on Github, but we haven't used those clients to implement support for popular ORMs.
Basically, the open-source ecosystem will need to add support for these ORMs but we will contribute wherever we can to push these initiatives. If we get lots of demand for a specific ORM, we will look into doing something special for that.
Hope that helps.
(disclaimer: I work on Cloud Spanner)