I decided to make a concerted effort to participate more on Twitter a few months back, but if you have a low number of followers hardly anyone interacts with you, it's like being in a big crowd where a few people have megaphones and everyone else is whispering. I suppose I could buy a bunch of followers for $ in order to seem more worth talking to but that's a bullshit tactic and I don't respect platforms where bullshit is rewarded. Twitter seems to function best as an adjunct to other media than as a self-sustaining ecosystem.
Frankly I feel Twitter has made the internet (and by extension, society) worse in numerous ways - the dumb 140 character limit (notwithstanding this being inherited from SMS), its appalling user interface, and the overuse of simplistic metrics to score everyone and everything they say, promoting the crudest sort of lowest-common-denominator social proof.
As far as I can see the best way to be popular on Twitter (other than already being famous to start with) is to be an ass, which will get social approval from people who feel the same way but are inhibited from expressing that for whatever reason. The good things about Twitter (speed and flatness) persist despite the other factors rather than as a result of them. If it shut down tomorrow I think people would get over the loss within a week.