I'd say it's best suited to people who don't have a family, sedentary lifestyle, or hobbies that require a lot of stuff.
In late 2007, I got rid of my place and everything I owned to travel indefinitely with only a laptop, HD cam, four shirts, a pair of pants, and two pair of underwear/socks. My worldly possessions weighed 14 lbs and occupied a backpack smaller than the L.L. Bean that hauled my books in high school.
Over the course of the preceding 6 months, I'd realized I never actually used my kitchen, living room, couch, TV, or pretty much anything else in my place. I would get home, play guitar and drums, use my computer, sleep, and leave.
So I got rid of it all, and the feeling was one of total liberation. I haven't looked back, and after 3 years (including a move to SF), I've added a small acoustic guitar and shed the HD cam.
I also realized that an apartment is mostly wasted space for someone who spends most of his time outside and around town, so I got rid of that too and sleep in my car.
Long story short, I've found getting rid of excess to be liberating, productive, and addictive. Highly recommended.