The Case for Taking a Very Little Bit of LSD Every Day – Mother Jones – Medium

What do you mean by anti-serotonin agent? One of LSD's (and many other classical psychedelics) primary mechanisms of action is as a serotonin receptor agonist. That means the psychoactive molecules enter the system and essentially behave like "extra" serotonin.

Also, taking it every day would quickly result in no effect. Tolerance builds extremely rapidly to psychedelics like LSD and psilocybin. Allowing at least a week between doses will ensure that tolerance is not a hindrance.

My perspective is that taking sub-psychedelic doses of LSD foster a feeling of having "arrived". There's nowhere else to be, so putting off projects or tasks seems silly; work, even the uncomfortable stuff, becomes more of an engaging puzzle or challenge, and there's a heightened awareness of the body that makes it trivially easy to make good choices (one just really wants to eat that fruit and use the standing desk that day).

Just one psychonaut's $0.02