A couple things:

I think Steve Yegge said this kind of thing a few years ago - namely that javascript is one of the most important programming languages today. I'm not saying that this invalidates the point, just that it was probably fairly apparent when he said it and, in my opinion, pretty obvious today.

Also, he mentions "And while we’re at it, maybe use it for desktop applications too?" which I think is interesting because Mozilla already has built a framework to do this kind of thing, with xulrunner. It's not based on V8 but newer builds do incorporate Mozilla's version of a javascript JIT, tracemonkey.