I won't claim any kind of expertise on the non-tech-related effects of TPP; I'm not an expert in international trade.
With respect to copyright, patent, and trademarks, however: I really don't care about "investors" who want to make other countries follow more draconian regimes in those areas. There's a happy medium between "zero acknowledgement of foreign copyrights at all" and "ridiculously excessive copyright laws"; ditto for patents and trademarks. TPP just directly exported the US's ludicrously excessive copyright, patent, and trademark laws, complete with DMCA-like provisions and criminal (not just civil) penalties. Those terms at a minimum needed fixing, and I think the people arguing against TPP in its current form on those grounds alone were right to do so.