Specifically, I think there's a chance that, worldwide, it will get more difficult to find places that basic food crops can be grown with sufficient reliability, due to extremes in heat, cold, storms, drought and flooding.
According to the data I've seen, on a worldwide average, this hasn't started happening yet, but it already happening in some regions.
What I'm concerned about is 'weather weirding'. On average, everything gets warmer, but because there's a lot more overall energy, the highs get higher, and the lows get lower, along with more extreme rain/flooding, along with more extreme drought. And, of course, a lot more intense storms.
I hope I am wrong, and it seems like the analysis of this line of thought is just starting to ramp up.
Anecdotally, it's why, for example, we got something like 10 or 12 '100 year' and '500 year' weather events in the US in 2016.