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For non-front-end developers, it's an important and useful tool, because it lets us build things without having to know CSS. But none of the experienced front-end developers I've ever worked with will use it, and most of them wince slightly when its name is mentioned.

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Bootstrap is a GUI framework for the web. It's like WPF or JavaFX but for HTML5 and JavaScript.

I wouldn't want to build a marketing website with Bootstrap but it provides web applications with a consistent look and feel.

All the teams I've been a part of use Bootstrap, including a lot of experienced front-end devs. Using SASS customization with Bootstrap really lets you hammer out a unique toolkit of common UI elements. However, my context is in web apps, not web sites. I could see strong reasoning for not bothering with Bootstrap for sites.

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