If I were starting up a 2D media company I might have some concern moving new hires from probably-familiar Adobe applications to the (excellent) Linux alternatives; but still probably not enough to dissuade me completely. For a new 3D studio the industry is so diverse anyway that it would be worth going with Blender to start with, or Maya if the heart desires it.
For software, I don't think there's a worthwhile platform which you can not develop for from Linux (aside apple nonsense, but even all-apple shops end up using OS X VMs for iOS builds since XCode build is highly stateful(!)).