LinkedIn + Outlook + Dynamics?
I would imagine real biological data isn't quite there yet, but it's certainly not for want of trying. Simulations might get pretty close. Blue Brain was aiming for 100M neurons and (presumably) a few orders of magnitude more connections and I think there's another simulation floating around with 10^11 neurons (but presumably less biophysical accuracy).
But yes, assuming your data is "big data" when it can easily be processed on a dev workstation or beefy server is very much in vogue right now.