If you are going to send transactional or marketing email, use Amazon SES, or Mandrill if you don't want to deal with setting up AWS SES. I had lost lot of my time trying to use the same email hosting for marketing purpose, don't recommend that to anyone.
For CRM, I really like https://insightly.com when I used it really helps me to get back on contacting users quickly, however if I have a bigger team in the future, I will try http://pipedrive.com.
But being real, 60% of the cases and spreadsheet and a share contact folder in Google using the Delegation option had been my day to day tool.
Alternatively Office 365 Business Premium. $12.50/month (12 month minimum commitment). Only reason you'd consider this is that it includes Email, Office Desktop Suite (Outlook, Word, Excel, etc), and CRM. Essentially you'd merge a couple of bills into one bill.
Both are alright support, good uptime, great vendor support, good scaling, and migration strategies (in and out).
PS - Yes, this is the "boring" and "obvious" answer but sometimes things are "boring" and "obvious" for a good reason.
I use Streak CRM as it integrates with gmail.
Email: Gmail / Amazon SES
Automation: DripEmails.com (I'm the founder)
For transactional email: Amazon SES
CRM: self-hosted SugarCRM
It isn't the cheaper but only the customer service worth it
They provvide also a good email sending limits (check it here http://docs.mailpoet.com/article/49-lists-of-hosts-and-their... )
"Multiple domain Backup MX mail server IMAP allows Real-time synchronization RoundCube, SquirrelMail and SOGo Web mail with support for languages right-to-left layout Anti-spam Spamassassin and Anti-virus ClamAV Contacts, Calendars and Tasks with CalDAV and CardDAV support Catch All, Alias, Forward, autoresponder, Sieve Filters Reliable and secure email hosting for companies, organizations, and individuals featuring WebMail, POP, IMAP and SMTP @ Contacts, Calendars and Tasks with CalDAV and CardDAV support @ Multiple domain hosting under the same account with no limitations @ Web-Administration area dedicated to individual user mailbox @ Anti-spam protections settings with per-user configuration"
At the moment there are some special servermx offers here : http://www.webhostingtalk.com/showthread.php?t=1621853
1 month of free trial cheers Max