I've got Clojure/Clojurescript, Rust, Python, HTML5 JavaScript, F#/C# and Java.
Clojure/Clojurescript is used for long running processes and web development. So backend/frontend stuff. I also use it for fun experiments, the REPL is great at that.
Rust is used when performance matters, when I want the simplicity of running a native executable with no heavy dependency, and when I need to write low level components.
Python is my goto scripting language for quick scripts, hacks, messing around. It also serves my scientific computing needs, data mining, visualization, etc. Also, this is the best language I've found for doing coding interviews or practice. So easy to whiteboard python.
HTML5 JavaScript is used for most web development, for customizing my editor Atom.io, and other things. With Metro apps, and other OS moving towards an HTML5 JavaScript stack, its also quite good at some user apps.
F# is good for simply knowing an ML language and when I want more functional flair in the .Net world.
C# and Java are used to pay the bills, as they are easiest to find jobs for.
There would be valid alternatives for most of those categories, but I highly recommend everyone invest in knowing one language for each one.
I haven't switched to Rust yet (I still deal with C/C++ at work on "legacy" code, and I'm having too much fun with Lua for my own stuff) but I don't expect to pick it up "quickly" and I'm sure I'll be trying to write C in Rust for some time. It comes with the territory.